LPAR6 : lysophosphatidic acid receptor 6

Description

The LPAR6 gene encodes for a G protein-coupled receptor (GPCR) that plays a crucial role in lipid metabolism, inflammation, and immune responses. It binds to lysophosphatidic acid (LPA), a bioactive lipid involved in various cellular processes. LPA signaling through LPAR6 has been implicated in diverse physiological functions, including cell growth, migration, and differentiation. The gene‘s expression is widely distributed, particularly in tissues like the heart, brain, and immune system, highlighting its potential significance in various biological processes.

Associated Diseases

• Cancer (e.g., breast, prostate, and lung cancer)
• Cardiovascular diseases (e.g., atherosclerosis)
• Neurological disorders (e.g., Alzheimer‘s disease)
• Immune disorders (e.g., inflammatory bowel disease)
• Metabolic disorders (e.g., obesity and diabetes)

Did you know?

LPAR6 has been linked to the development of cancer and may represent a promising target for novel cancer therapies.