KRT25
Description
KRT25, also known as cytokeratin 25, is a type II keratin protein primarily expressed in the suprabasal layers of the epidermis. It forms an integral part of the keratin filament network, contributing to skin structural integrity, barrier function, and cell adhesion. KRT25 plays a crucial role in maintaining skin homeostasis and protecting against environmental stressors. Mutations in the KRT25 gene can lead to various skin disorders, highlighting its importance in skin health.
Associated Diseases
Did you know?
KRT25 is particularly abundant in the palms and soles, which explains its involvement in disorders affecting these areas.
