AMELX : amelogenin X-linked
Description
The AMELX (amelogenin X-linked) is a protein-coding gene located on chromosome X.
The AMELX gene provides instructions for making amelogenin, a protein vital for normal tooth development. Amelogenin is involved in the formation of enamel, the hard, white outer layer of teeth. Enamel is primarily composed of mineral crystals, arranged in organized bundles that contribute to its strength and durability. Although its exact function is not fully understood, amelogenin seems to separate and support these crystals as they grow. Once the crystals are mature, amelogenin is removed, leaving enamel with very little protein. The AMELX gene resides on the X chromosome, producing nearly all the body's amelogenin. The Y chromosome also carries a copy of the amelogenin gene (AMELY), but it produces very little amelogenin and is not essential for enamel formation.
AMELX is also known as AI1E, AIH1, ALGN, AMG, AMGL, AMGX.
