DENND2D

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Description

The DENND2D (DENN domain containing 2D) is a protein-coding gene located on chromosome 1.

DENND2D acts as a guanine nucleotide exchange factor (GEF), specifically for the Rab proteins RAB9A and RAB9B. This means it facilitates the exchange of GDP (guanosine diphosphate) for GTP (guanosine triphosphate) on these Rab proteins. This conversion activates the Rab proteins, transforming them from their inactive GDP-bound state to their active GTP-bound state.

DENND2D is also known as -.

Associated Diseases