DCK
Description
The DCK (deoxycytidine kinase) is a protein-coding gene located on chromosome 4.
DCK may refer to deoxycytidine kinase, an enzyme involved in nucleotide metabolism.
Deoxycytidine kinase (dCK) phosphorylates the deoxyribonucleosides deoxycytidine, deoxyguanosine and deoxyadenosine. It has broad substrate specificity and does not display selectivity based on the chirality of the substrate. dCK is also an essential enzyme for the phosphorylation of numerous nucleoside analogs widely employed as antiviral and chemotherapeutic agents.
DCK is also known as -.
Associated Diseases
- common variable immunodeficiency
- isolated agammaglobulinemia
- combined immunodeficiency with skin granulomas
- immunodeficiency 18
- reticular dysgenesis
- BENTA disease
- severe combined immunodeficiency due to CTPS1 deficiency
- immunodeficiency 62
- immunodeficiency 99 with hypogammaglobulinemia and autoimmune cytopenias
- severe combined immunodeficiency due to IKK2 deficiency
