DAZ4
DAZ4: A Crucial Gene for Male Fertility
Description
DAZ4 (Deleted in Azoospermia-4) is a gene located on the Y chromosome that is essential for male fertility. It encodes a protein that plays a vital role in the production of sperm. The DAZ4 gene produces a protein called DAZ4, which is responsible for the production of a number of proteins that are essential for the development of sperm. Mutations in the DAZ4 gene can lead to a number of fertility problems, including azoospermia (the absence of sperm in the semen) and oligospermia (a low sperm count).
Associated Diseases
DAZ4 mutations have been associated with a number of fertility problems in men, including:
- Azoospermia
- Oligospermia
- Asthenozoospermia (poor sperm motility)
- Teratozoospermia (abnormal sperm morphology)
Did you Know ?
DAZ4 mutations are estimated to be responsible for approximately 10% of cases of male infertility.