CRYZ
Description
The CRYZ (crystallin zeta) is a protein-coding gene located on chromosome 1.
The CRYZ gene encodes a protein known as quinone oxidoreductase, which is classified as a taxon-specific crystallin. While crystallins are primarily known for maintaining the transparency and refractive index of the vertebrate eye lens, CRYZ exhibits distinct features. It possesses NADPH-dependent quinone reductase activity, differentiating it from other known quinone reductases. Despite its similarity to the zinc-containing alcohol dehydrogenase family, CRYZ lacks alcohol dehydrogenase activity. Notably, lens expression of CRYZ is low in humans, unlike other mammalian species. One pseudogene associated with CRYZ has been identified.
CRYZ is also known as -.
