CPEB2-AS1
Title: CPEB2-AS1: Unraveling the Mysterious Long Non-Coding RNA
Introduction
In the intricate tapestry of genetics, beyond the realm of protein-coding genes, lies a fascinating world of non-coding RNA molecules. Among these, long non-coding RNAs (lncRNAs) have emerged as key players in regulating gene expression and biological processes. One such lncRNA that has garnered significant attention is CPEB2-AS1. Join us as we delve into the realm of CPEB2-AS1, exploring its enigmatic role in health and disease.
Description
CPEB2-AS1 is a lncRNA located on the opposite strand of the CPEB2 gene on chromosome 19. LncRNAs are transcripts that lack protein-coding potential, but they possess a remarkable ability to interact with other molecules, influencing gene expression and cellular function.
Associated Diseases
Research has implicated CPEB2-AS1 in various human diseases, including:
- Cancer: CPEB2-AS1 has been found to promote tumor growth and metastasis in multiple cancers, such as gastric, colorectal, and breast cancer.
- Cardiovascular Diseases: Elevated levels of CPEB2-AS1 have been linked to cardiac fibrosis, a condition characterized by excessive scarring of the heart tissue.
- Neurological Disorders: CPEB2-AS1 dysregulation has been associated with neurodegenerative diseases like Alzheimer's and Parkinson's diseases.
Did you Know ?
Studies have shown that CPEB2-AS1 levels are significantly upregulated in over 80% of gastric cancer cases, suggesting its potential as a diagnostic and prognostic biomarker for this disease.