CORO6
Description
The CORO6 (coronin 6) is a protein-coding gene located on chromosome 17.
Coronin-6, also known as coronin-like protein E (Clipin-E), is a protein that in humans is encoded by the CORO6 gene. It belongs to the coronin family, which are actin binding proteins. The CORO6 gene is located on chromosome 17 at the cytogenetic band 17 p11.2. CORO6 is well conserved across various eukaryotic organisms, including animals and fungi.
Expression
- EST profile: Based on the EST profile, CORO6 is highly expressed in the larynx, nerve, and muscle. It is also highly expressed in breast (mammary gland) tumors.
- Human Development: CORO6 is expressed at higher levels during the blastocyst stage and in adults.
Transcript Variant: Alternative mRNAs are shown aligned from 5' to 3' on a virtual genome where introns have been shrunk to a minimal length. Exon size is proportional to length, and intron height reflects the number of cDNAs supporting each intron. Introns of the same color are identical, and those of different colors are different.
Coronin-6, also known as Coronin-like protein E (Clipin-E), is an actin-binding protein that plays a role in various cellular processes, including actin cytoskeleton organization, cell motility, and signal transduction. It is highly expressed in the larynx, nerve, and muscle tissues, and is also found in high levels in breast tumors. Coronin-6 is highly conserved across eukaryotic organisms, suggesting its importance in fundamental cellular functions.
CORO6 is also known as ClipinE.
