COLCA1
Description
The COLCA1 (colorectal cancer associated 1) is a ncRNA gene located on chromosome 11.
COLCA1 is a gene that encodes the alpha 1 chain of type I collagen. Type I collagen is the most abundant collagen in the human body and is essential for the structure and function of various tissues including skin, bone, tendon, and ligament. Mutations in COLCA1 can cause various genetic disorders such as osteogenesis imperfecta (brittle bone disease) and Ehlers-Danlos syndromes.
COLCA1, also known as collagen alpha-1 chain A, is a protein that plays a crucial role in the formation and maintenance of collagen fibrils, which are essential for the structural integrity of various tissues, including bones, tendons, ligaments, and skin. Its primary function is to provide tensile strength and support to these tissues.
COLCA1 is also known as C11orf92, CASC12, LOH11CR1F.
