CLEC4G
Description
The CLEC4G (C-type lectin domain family 4 member G) is a protein-coding gene located on chromosome 19.
CLEC4G binds to sugars like mannose, N-acetylglucosamine (GlcNAc), and fucose in a calcium-dependent manner, but does not bind to galactose, as shown in laboratory studies.
CLEC4G is also known as DTTR431, LP2698, LSECtin, UNQ431.
Associated Diseases
- primary familial polycythemia due to EPO receptor mutation
- beta-thalassemia-X-linked thrombocytopenia syndrome
- hemolytic anemia due to diphosphoglycerate mutase deficiency
- X-linked severe congenital neutropenia
- neutropenia, severe congenital, 2, autosomal dominant
- macrothrombocytopenia, isolated, 2, autosomal dominant
- erythrocytosis, familial, 6
- X-linked sideroblastic anemia 1
- erythrocytosis, familial, 3
- thrombocythemia 2
- transient myeloproliferative syndrome
- thrombocytopenia 4
- thrombocytopenia 2
- neutropenia, severe congenital, 1, autosomal dominant
