CENPO
Description
CENPO, a protein crucial for proper chromosome segregation during cell division, plays a vital role in the assembly and function of the centromere, the region on a chromosome responsible for attaching to microtubules during mitosis and meiosis. CENPO‘s interaction with other proteins, including CENP-A and CENP-C, ensures the accurate separation of chromosomes, preventing aneuploidy and maintaining genetic stability. The gene encoding CENPO is highly conserved across various species, highlighting its fundamental importance in eukaryotic cell division.
Associated Diseases
Did you know?
CENPO has been shown to be involved in the regulation of the spindle assembly checkpoint, a mechanism that ensures proper chromosome alignment before cell division.
