CDC42EP3

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Description

The CDC42EP3 (CDC42 effector protein 3) is a protein-coding gene located on chromosome 2.

Cdc42 effector protein 3 is a protein encoded by the CDC42EP3 gene in humans. It is part of the Borg family of CDC42 effector proteins, characterized by a CRIB domain. This protein binds to and negatively regulates the function of CDC42. It can interact with CDC42 and ARHQ/TC10. Expression of CDC42EP3 in fibroblasts leads to the formation of pseudopodia.

CDC42EP3 has been shown to interact with CDC42 and RHOQ.

CDC42EP3 is also known as BORG2, CEP3, UB1.

Associated Diseases