CCDC92
Description
The CCDC92 (coiled-coil domain containing 92) is a protein-coding gene located on chromosome 12.
CCDC92, or Limkain beta-2, is a protein encoded by the CCDC92 gene in humans. It likely participates in DNA repair or reduction/oxidation reactions. The gene is ubiquitously expressed in humans and highly conserved across animals. The CCDC92 gene is located on chromosome 12 at position 12q24.31, spanning 36,576 bases and containing nine exons. It codes for a 331 amino-acid protein. The protein localizes to the nucleus and contains a coiled-coil domain (amino acids 23-82) with an unknown function. CCDC92 is rich in histidine and glutamic acid but deficient in phenylalanine. It has a molecular weight of 37 kDa, an isoelectric point of 9.3, and lacks charged, hydrophobic, or transmembrane domains. Predicted phosphorylation sites are conserved at S211, S325, T21, T52, T122, and Y130, while conserved glycosylation sites are found at S183 and T244. The protein exhibits a large alpha helical section near the beginning, extending to the middle, followed by two smaller helical sections near the end.
CCDC92 is also known as -.
