CBWD2
Cannabinoid Receptor 2 (CB2): The Body's Natural Pain Reliever
Description
Cannabinoid receptor 2 (CB2) is a G protein-coupled receptor that belongs to the endocannabinoid system (ECS), a complex network of neurotransmitters and receptors found throughout the body. CB2 receptors are primarily expressed in immune cells, including macrophages, microglia, and lymphocytes. They play a crucial role in regulating inflammation, pain, and immune responses.
Associated Diseases
The activation of CB2 receptors has been linked to the treatment and management of various conditions, including:
- Chronic Pain: CB2 receptors modulate pain perception by reducing the release of inflammatory mediators and enhancing the production of anti-inflammatory substances.
- Inflammation: CB2 receptors suppress inflammation by inhibiting the production of pro-inflammatory cytokines and chemokines.
- Neurodegenerative Diseases: CB2 receptors have neuroprotective effects and may play a role in reducing inflammation and promoting neural survival in diseases such as Alzheimer's and Parkinson's.
- Autoimmune Diseases: CB2 receptor agonists have shown promise in treating autoimmune diseases by modulating immune responses and suppressing inflammation.
- Cancer: CB2 receptors are expressed in various cancer cells and their activation may inhibit tumor growth and metastasis.
Did you Know ?
According to a study published in the journal Pain, activation of CB2 receptors in mice has been shown to reduce chronic pain by up to 90%.
