RIT1 : Ras like without CAAX 1
Description
The RIT1 (Ras like without CAAX 1) is a protein-coding gene located on chromosome 1.
The RIT1 gene provides instructions for producing a protein that assists cells in surviving stressful conditions, such as high energy demands. As part of the RAS/MAPK signaling pathway, RIT1 relays signals from outside the cell to the cell's nucleus, instructing the cell to grow, divide, or mature and specialize. RIT1 is a GTPase, converting GTP to GDP. It is activated by GTP binding, transmitting signals during stress, and deactivated by converting GTP to GDP, ceasing signal relay. RIT1 belongs to the oncogene family, potentially causing normal cells to become cancerous. It is part of the Ras oncogene family, which includes KRAS, HRAS, and NRAS, all playing important roles in cell division, differentiation, and apoptosis.
RIT1 is also known as NS8, RIBB, RIT, ROC1.
