AACS
Description
The AACS gene encodes for acetoacetyl-CoA synthetase, an enzyme crucial for the metabolism of cholesterol. It plays a key role in the initial steps of ketogenesis, the process of generating ketones from fatty acids, which serve as an alternative energy source for the body. AACS also influences the synthesis of bile acids, which are essential for the digestion and absorption of fats. Variations in the AACS gene have been linked to alterations in cholesterol levels, potentially impacting cardiovascular health.
Associated Diseases
Did you know?
AACS is also involved in the biosynthesis of the steroid hormone testosterone, highlighting its broad impact on metabolism and human health.
