PERP

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The PERP gene encodes a protein called p53 regulatory protein. This protein acts like a co-pilot alongside the famous tumor suppressor p53. PERP helps stabilize p53, allowing it to effectively identify and repair DNA damage or trigger cell death in severely damaged cells.

Associated Diseases

Erythrokeratodermia variabilis et progressiva, Olmsted syndrome-2, Cancers

Did you know

Mutations in PERP can disrupt its interaction with p53, hindering its ability to suppress tumors. This can increase the risk of developing various cancers.