CDK12

CDK12 gene plays a crucial role in regulating cell division and gene expression

Associated Diseases

 Prostate cancer and Ovarian cancer

Did you know

The CDK12 gene, or Cyclin-Dependent Kinase 12 gene, encodes a protein kinase that plays a crucial role in regulating cell division and gene expression. It is involved in the transcriptional regulation of genes related to DNA repair and cell cycle progression. Mutations in the CDK12 gene have been implicated in various cancer types, particularly prostate cancer and ovarian cancer. These mutations can disrupt normal cellular functions, leading to genomic instability and tumor development. Understanding the role of the CDK12 gene in cancer biology is important for developing targeted therapies and personalized treatment strategies. Additionally, CDK12 inhibitors are being investigated as potential anticancer agents, offering new avenues for cancer treatment research.