CA5B
Description
The CA5B (carbonic anhydrase 5B) is a protein-coding gene located on chromosome X.
Carbonic anhydrase 5B, mitochondrial is an enzyme encoded by the CA5B gene in humans. Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide and play a role in various biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They exhibit diverse tissue distribution and subcellular localization. CA VB resides in the mitochondria and shares the highest sequence similarity with CA VA, another mitochondrial CA. Unlike CA VA, which is confined to the liver, CA VB has a broader tissue distribution. This difference in tissue distribution suggests that the two mitochondrial carbonic anhydrases have evolved to fulfill distinct physiological functions.
CA5B is also known as CA-VB, CAVB.
