C4B_2
Description
The C4B_2 (complement component 4B (Chido/Rodgers blood group), copy 2) is a protein-coding gene located on chromosome 6.
C4B gene encodes a protein that participates in the complement system, a key part of the innate immune system. It plays a role in the classical and lectin pathways of complement activation, binding to antigen-antibody complexes and initiating a cascade of reactions leading to the formation of the membrane attack complex (MAC). This complex then lyses foreign cells, such as bacteria and viruses.
C4B, also known as complement component 4B, is a protein that in humans is encoded by the C4B gene. This gene is located on chromosome 6 and is part of the complement system, a crucial part of the innate immune system. C4B plays a key role in the classical and lectin pathways of complement activation. It binds to antigen-antibody complexes, forming a complex called C4b2a that initiates a cascade of reactions leading to the formation of the membrane attack complex (MAC). This complex can then lyse foreign cells, such as bacteria and viruses. C4B also contributes to the clearance of immune complexes, helping to prevent autoimmunity. Mutations in the C4B gene can lead to deficiencies in the complement system, which can increase susceptibility to infections and autoimmune diseases.
C4B_2 is also known as -.
