C22orf29
c22orf29: A Gene with Potential Roles in Neurological Disorders
Description
c22orf29 is a gene located on chromosome 22q11.21. It encodes a protein known as C22orf29 or chromosome 22 open reading frame 29. The exact function of C22orf29 is not yet fully understood, but its involvement in neurological processes is gaining increasing attention.
Associated Diseases
Mutations in the c22orf29 gene have been found to be associated with several neurological disorders, including:
- Schizophrenia: Mutations in c22orf29 have been linked to an increased risk of developing schizophrenia, a complex mental disorder characterized by hallucinations, delusions, and disorganized thinking.
- Bipolar disorder: Some studies have suggested that c22orf29 variants may also contribute to the development of bipolar disorder, which involves episodes of mania alternating with periods of depression.
- Autism spectrum disorder (ASD): Researchers have identified mutations in c22orf29 in individuals with ASD, a neurodevelopmental condition characterized by difficulties with social interaction and communication.
- Intellectual disability: Mutations in c22orf29 have been linked to intellectual disability, a condition resulting in significant cognitive impairments.
Did you Know ?
According to a study published in the American Journal of Psychiatry, approximately 1% of individuals with schizophrenia have mutations in the c22orf29 gene. This finding highlights the potential role of c22orf29 in the development of this devastating disorder.
