C1orf100
C1orf100: An Intriguing Gene with Uncertain Origins and Diverse Implications
Description
C1orf100 is a human gene located on chromosome 1, specifically at locus 1p13.1. It spans approximately 140 kilobases of DNA and encodes a protein of 497 amino acids. The function of C1orf100 protein remains elusive, but recent research suggests its involvement in various cellular processes.
Associated Diseases
Mutations in C1orf100 have been implicated in several human diseases, including:
- Type 2 Diabetes: Mutations in C1orf100 increase the risk of developing type 2 diabetes, a chronic metabolic disorder characterized by elevated blood glucose levels.
- Obesity: C1orf100 has been linked to obesity as well, particularly visceral fat accumulation.
- Cardiovascular Disease: Mutations in C1orf100 may contribute to the development of cardiovascular diseases such as coronary artery disease and atherosclerosis.
- Neurological Disorders: Some studies suggest that C1orf100 may play a role in neurological disorders like schizophrenia and bipolar disorder.
Did you Know ?
A recent genome-wide association study identified variants in the C1orf100 gene as one of the strongest genetic risk factors for type 2 diabetes. These variants were found to increase the risk of developing the condition by up to 30%.
