C19orf45
c19orf45: A Gene Linked to Mental Health and Neurodegenerative Disorders
Description
c19orf45, also known as chromosome 19 open reading frame 45, is a gene located on chromosome 19 in humans. It encodes a protein known as chromosome 19 open reading frame 45 protein (C19ORF45). This protein is involved in various cellular processes, including RNA metabolism and protein synthesis.
Associated Diseases
Mutations in the c19orf45 gene have been linked to several mental health and neurodegenerative disorders, including:
- Schizophrenia: Studies have found an association between specific variants of the c19orf45 gene and an increased risk of schizophrenia.
- Autism spectrum disorder (ASD): Mutations in c19orf45 have been identified in individuals with ASD.
- Intellectual disability: Some individuals with intellectual disability have been found to carry mutations in the c19orf45 gene.
- Alzheimer's disease: Recent research suggests that c19orf45 may play a role in the development and progression of Alzheimer's disease.
Did you Know ?
Research has shown that approximately 1 in 10,000 people worldwide carry a mutation in the c19orf45 gene. This mutation can increase the risk of developing mental health disorders and neurodegenerative diseases.
