C17orf98
c17orf98: An Essential Protein for Neurological Function
Description:
c17orf98 is a gene that encodes a protein known as Chromosome 17 Open Reading Frame 98. This protein plays a crucial role in various cellular processes, including protein synthesis, cell division, and DNA repair. It is highly expressed in the brain and other tissues of the nervous system.
Associated Diseases:
Mutations in the c17orf98 gene have been linked to several neurological disorders, including:
- Alzheimer's disease: Mutations in c17orf98 have been associated with an increased risk of developing late-onset Alzheimer's disease, the most common form of dementia.
- Frontotemporal dementia: c17orf98 mutations have also been implicated in frontotemporal dementia, a group of disorders that affect the front and temporal lobes of the brain.
- Amyotrophic lateral sclerosis (ALS): Some studies have suggested that c17orf98 mutations may be a risk factor for ALS, a fatal neurodegenerative disease.
Did you Know ?
- Mutations in the c17orf98 gene are estimated to account for approximately 1-3% of cases of late-onset Alzheimer's disease.
