BCYRN1
Description
The BCYRN1 (brain cytoplasmic RNA 1) is a ncRNA gene located on chromosome 2.
BCYRN1, also known as BC200 lncRNA, is a 200 nucleotide RNA transcript predominantly found in the brain. It is a long non-coding RNA (lncRNA), belonging to a large family of RNA transcripts not translated into protein. LncRNAs are transcripts of 200 nucleotides or longer and are more prevalent than protein-coding genes. BCYRN1 plays a role in translation regulation by inhibiting its initiation. It has also been implicated in various forms of cancer and Alzheimer's disease. The BCYRN1 gene is located on chromosome 2p16 and is characterized by a repeat polymorphism of cytosines and adenines (CA) near its location. The 5' region of BCYRN1 contains monomeric Alu short interspersed repetitive elements (SINEs) that allow for its transposition and have been conserved in other primates.
BCYRN1 is also known as BC200, BC200a, LINC00004, NCRNA00004.
Associated Diseases
- cancer
- urinary bladder carcinoma
- leukodystrophy
- Parkinson disease
- Ehlers-Danlos syndrome, musculocontractural type
- T-cell non-Hodgkin lymphoma
- breast cancer
