BCL7A
Description
The BCL7A (BAF chromatin remodeling complex subunit BCL7A) is a protein-coding gene located on chromosome 12.
The BCL7A gene is located on chromosome 12 (specifically at the 12q24.31 band). It encodes a protein that's part of the SWI/SNF complex, which plays a role in regulating how DNA interacts with histones. This gene has been found to be mutated in lymphomas and silenced in blood cancers. These changes are thought to contribute to the development of these diseases.
The BCL7A gene encodes a protein that is part of the SWI/SNF complex, a group of proteins that can change how DNA interacts with histones using energy from ATP breakdown. This gene is often found mutated in lymphomas and silenced in blood cancers due to a process called promoter hypermethylation.
BCL7A is also known as BCL7, SMARCJ1.
