BRCA1-associated RING domain protein 1, associated with breast and ovarian cancer.

Associated Diseases

Breast and Ovarian Cancer

Did you know

BARD1 mutations are associated with a small percentage of breast and ovarian cancer cases. The BARD1 gene, or BRCA1-associated RING domain protein 1, is located on chromosome 2q35 and encodes a protein that interacts with the BRCA1 tumor suppressor protein to form a complex involved in various cellular processes, including DNA repair, cell cycle regulation, and apoptosis (programmed cell death). BARD1 plays a critical role in maintaining genomic stability and suppressing tumorigenesis.

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