BRCA1-associated protein 1, linked to uveal melanoma and mesothelioma.

Associated Diseases

Uveal Melanoma, Mesothelioma

Did you know

BAP1-associated cancers are rare, with a prevalence of about 1 in 1 million. The BAP1 gene, or BRCA1-associated protein 1, is located on chromosome 3p21.1 and encodes a tumor suppressor protein that plays a crucial role in regulating various cellular processes, including DNA repair, cell cycle control, and apoptosis (programmed cell death). BAP1 is involved in removing ubiquitin molecules from specific protein targets, thereby modulating their activity and stability.

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