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Mastocytosis: A Comprehensive Guide
Description
Mastocytosis is a rare disorder characterized by an abnormal proliferation of mast cells, which are immune cells that play a role in allergic reactions. Mast cells release histamine and other inflammatory mediators when activated, leading to a range of symptoms. Mastocytosis can affect both children and adults and can manifest in various forms.
Associated Diseases
Mastocytosis is often associated with other diseases, including:
- Gastrointestinal disorders: Ulcerative colitis, Crohn's disease
- Endocrine disorders: Thyroid disease, Cushing's syndrome
- Immunological disorders: Autoimmune diseases, allergic diseases
- Myeloproliferative disorders: Leukemia, myelodysplastic syndromes
- Neurological disorders: Epilepsy, migraines
Did you Know ?
Approximately 1 in 10,000 people worldwide are diagnosed with mastocytosis, making it a relatively uncommon condition. However, the prevalence may be underestimated due to underdiagnosis and misdiagnosis.