ADD3-AS1
Description
ADD3-AS1, also known as ADIPOR1-AS1, is a long non-coding RNA (lncRNA) located on chromosome 17. LncRNAs are RNA molecules that do not code for proteins but play crucial roles in regulating gene expression. ADD3-AS1 has been implicated in various cellular processes, including cell proliferation, apoptosis, and inflammation, often through interactions with other molecules like microRNAs.
Associated Diseases
- Cancer: ADD3-AS1 is dysregulated in several types of cancer, such as lung cancer, colorectal cancer, and gastric cancer, where it may act as an oncogene or tumor suppressor depending on the context.
- Cardiovascular disease: Studies suggest ADD3-AS1 may play a role in heart disease, particularly in cardiomyocyte hypertrophy and angiogenesis.
- Neurological disorders: ADD3-AS1 has been associated with neurological disorders like Alzheimer‘s disease and Parkinson‘s disease, but its precise function in these conditions remains under investigation.
- Inflammatory disorders: ADD3-AS1 has been linked to inflammation and immune responses, indicating potential roles in autoimmune diseases.
Did you know?
ADD3-AS1 exhibits tissue-specific expression patterns, suggesting its role may vary across different organs.
