ACTR8
Description
The ACTR8 (actin related protein 8) is a protein-coding gene located on chromosome 3.
ACTR8 plays a crucial role in the proper arrangement of chromosomes during cell division (mitosis). It has limited ATP-driven energy activity and cannot form long chains (polymerize).
ACTR8 is also known as ARP8, INO80N, hArp8.
Associated Diseases
- ovarian cancer
- hemoglobin E-beta-thalassemia syndrome
- hemoglobin D disease
- primary familial polycythemia due to EPO receptor mutation
- hereditary persistence of fetal hemoglobin-sickle cell disease syndrome
- microcytic anemia with liver iron overload
- familial pseudohyperkalemia
- lysosomal storage disease
- alpha thalassemia-intellectual disability syndrome type 1
- dominant beta-thalassemia
- hemolytic anemia due to diphosphoglycerate mutase deficiency
- delta-beta-thalassemia
- cryohydrocytosis
- hemoglobin E disease
