ACAN : aggrecan
Title: Delving into the World of Aggrecan: The Protein Behind Cartilage Strength
Description:
Aggrecan, the workhorse protein of cartilage, plays a crucial role in shaping our bodies. This proteoglycan, adorned with sugar molecules, is the mastermind behind cartilage's exceptional strength and resilience. Discover the fascinating world of aggrecan, its vital functions, and its impact on our musculoskeletal system.
Associated Diseases:
Dysfunctional aggrecan can lead to several debilitating conditions, including:
- Osteoarthritis: A common joint disorder characterized by cartilage breakdown and inflammation.
- Spondyloepiphyseal Dysplasia: A genetic disorder that affects cartilage and bone development, causing skeletal abnormalities.
- Congenital Heart Defects: Aggrecan mutations have been linked to certain congenital heart defects.
Did you Know ?
Aggrecan constitutes over 90% of the proteoglycan content in cartilage, highlighting its indispensable role in maintaining cartilage health.
