ACACB


Description

The ACACB gene provides instructions for making acetyl-CoA carboxylase beta, an enzyme that plays a crucial role in fatty acid biosynthesis. This enzyme catalyzes the first committed step in this process, converting acetyl-CoA to malonyl-CoA. This conversion is vital for the body‘s ability to store energy as fat and synthesize essential fatty acids. The ACACB gene is expressed in various tissues, including the liver, adipose tissue, and mammary glands, where fatty acid synthesis is particularly active.

Associated Diseases

Did you know?

The ACACB gene is highly regulated by insulin, a hormone that promotes energy storage. When insulin levels are high, the ACACB gene is activated, leading to increased fatty acid synthesis.


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