ACACA
Description
The ACACA gene encodes acetyl-CoA carboxylase alpha (ACCα), a crucial enzyme in the biosynthesis of fatty acids. ACCα catalyzes the irreversible carboxylation of acetyl-CoA to malonyl-CoA, a committed step in fatty acid synthesis. This process is essential for various cellular functions, including energy storage, membrane formation, and hormone production. ACCα activity is tightly regulated by factors like insulin, glucagon, and dietary fat intake, ensuring proper balance between fatty acid synthesis and breakdown.
Associated Diseases
Did you know?
ACCα is a large, multi-domain enzyme with a complex structure that allows for tight regulation of its activity.
