ABTB1
Description
The ABTB1 gene encodes a protein known as ankyrin repeat and BTB (Broad-Complex, Tramtrack, Bric a brac) domain containing protein 1. This protein plays a crucial role in a variety of cellular processes, including transcription regulation, protein degradation, and cell growth. Its versatility arises from its ability to interact with numerous other proteins, forming complex regulatory networks that influence cellular behavior. ABTB1 dysfunction has been implicated in several disease conditions, underscoring its significance in maintaining cellular homeostasis.
Associated Diseases
- Cancer (including leukemia, lymphoma, and breast cancer)
- Neurodevelopmental disorders (including autism spectrum disorder and intellectual disability)
- Cardiovascular disease
Did you know?
ABTB1 has been shown to interact with the tumor suppressor protein p53, playing a role in regulating p53 activity and contributing to cancer development.
