ABLIM2
Understanding Ablim2: A Key Player in the Immune System
Description
Ablim2 (actin-binding LIM protein 2) is a protein that plays a vital role in the function of the immune system. It is primarily expressed in immune cells, including T cells, B cells, and macrophages. Ablim2 is involved in various cellular processes, such as cell migration, adhesion, and signaling.
Associated Diseases
Ablim2 has been associated with several diseases, including:
- Autoimmune diseases: Ablim2 deficiency has been linked to an increased risk of developing autoimmune diseases, such as lupus and rheumatoid arthritis. In these conditions, the immune system mistakenly attacks the body's own tissues.
- Cancer: Ablim2 has been found to play a role in the development and progression of certain types of cancer, such as breast cancer, lung cancer, and leukemia.
- Inflammatory diseases: Ablim2 is involved in the regulation of inflammation. Its deficiency has been associated with increased inflammation in diseases such as Crohn's disease and ulcerative colitis.
Did you Know ?
Studies have shown that individuals with a genetic variation in the Ablim2 gene have a 20% higher risk of developing an autoimmune disease.
