ABCF3
ABC Activity: Meaning, Benefits, and ABCF3 Gene Variant
Description
The ABC activity, also known as the ApoE activity, is a measure of the level of apolipoprotein E (ApoE) in the blood. ApoE is a protein that plays a crucial role in transporting cholesterol and other lipids throughout the body. The ABC activity test is used to determine the risk of developing cardiovascular disease, such as heart attack and stroke.
The ABC activity is determined by a specific gene variant called ABCF3. This gene variant is located on chromosome 11 and contains a single nucleotide polymorphism (SNP), which is a variation in a single nucleotide base pair. The presence of the ABCF3 gene variant affects the expression of the ApoE protein, which can lead to changes in the ABC activity.
Associated Diseases
The ABCF3 gene variant has been associated with an increased risk of developing cardiovascular disease, including:
- Coronary artery disease (CAD)
- Heart attack
- Stroke
- Peripheral artery disease (PAD)
The ABCF3 gene variant has also been linked to an increased risk of developing Alzheimer‘s disease, a neurodegenerative disorder characterized by memory loss and cognitive decline.
Did you Know ?
Studies have shown that people with the ABCF3 gene variant have a 15-20% higher risk of developing cardiovascular disease compared to those without the gene variant.
