The AADAC gene encodes the enzyme arylacetamide deacetylase, which is involved in the metabolism of certain drugs and the biotransformation of arylamine and heterocyclic amine carcinogens.

Associated Diseases

It is associated with diseases such as Gilles De La Tourette Syndrome and Chronic Tic Disorder. Additionally, variations in AADAC expression have been studied for their potential impact on the prognosis of certain cancers, including advanced gastric cancer. The gene plays a role in lipid metabolism and is linked to pathways like oxidation by cytochrome P450 and Phase I and II biotransformation.

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