PMP2


Description

The PMP2 (peripheral myelin protein 2) is a protein-coding gene located on chromosome 8.

Myelin P2 protein is a protein that in humans is encoded by the PMP2 gene. Myelin protein P2 is a constituent of peripheral nervous system (PNS) myelin, also present in small amounts in central nervous system (CNS) myelin. As a structural protein, P2 is thought to stabilize the myelin membranes, and may play a role in lipid transport in Schwann cells. Structurally, P2 belongs to the family of cytoplasmic fatty acid-binding proteins (FABPs).

May play a role in lipid transport in Schwann cells. May bind cholesterol.

PMP2 is also known as CMT1G, FABP8, M-FABP, MP2, P2.

Associated Diseases



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