PALM
Description
The PALM (paralemmin) is a protein-coding gene located on chromosome 19.
Paralemmin is a protein encoded by the PALM gene in humans. It belongs to the paralemmin protein family, which includes CAP-23, GAP-43, MARCKS, and MacMARCKS. This protein is prenylated and palmitoylated, associating with the cytoplasmic face of plasma membranes. It is involved in plasma membrane dynamics in neurons and other cell types. Multiple alternatively spliced transcript variants have been identified, but only two have been fully characterized.
PALM is also known as PALM1.
Associated Diseases
- diabetes mellitus, transient neonatal, 2
- hyperlipoproteinemia type V
- cholesterol-ester transfer protein deficiency
- hypertriglyceridemia 2
- coronary artery disease, autosomal dominant 2
- pancreatic triacylglycerol lipase deficiency
- colorectal cancer
- cancer
