GABBR2
GABBR2: A Key Player in Neurology and Psychiatry
Description
GABBR2 (gamma-aminobutyric acid (B) receptor subunit 2) is a protein that plays a crucial role in the brain's inhibitory neurotransmission system. It is a subunit of the GABAB receptor, which is responsible for mediating the effects of the inhibitory neurotransmitter GABA. GABA is involved in a wide range of brain functions, including synaptic plasticity, cognition, and mood regulation.
Associated Diseases
Mutations in GABBR2 have been linked to a number of neurological and psychiatric disorders, including:
- Epilepsy
- Autism spectrum disorder
- Intellectual disability
- Anxiety disorders
- Depression
- Schizophrenia
Did you Know ?
Approximately 1% of individuals with epilepsy have a mutation in GABBR2.
