BRWD3
Description
The BRWD3 (bromodomain and WD repeat domain containing 3) is a protein-coding gene located on chromosome X.
BRWD3 (Bromodomain and WD repeat-containing protein 3) is a human protein encoded by the BRWD3 gene. It contains a bromodomain and several WD repeats, suggesting a role in chromatin modification and transcription. Mutations in BRWD3 can lead to mental retardation or permanent paralysis X-linked type 93, also known as mental retardation X-linked with macrocephaly. Additionally, BRWD3 is linked to translocations in B-cell chronic lymphocytic leukemia.
BRWD3 is involved in regulating cell morphology and cytoskeletal organization. It is essential for controlling cell shape.
BRWD3 is also known as BRODL, MRX93, XLID93.
