ATRN
Description
The ATRN (attractin) is a protein-coding gene located on chromosome 20.
Attractin is a protein encoded by the ATRN gene in humans. It belongs to the Group XI C-type lectin family and exists in multiple isoforms. One isoform is a membrane-bound protein similar to the mouse mahogany protein, a receptor involved in obesity regulation. Another isoform is a secreted protein that participates in the initial immune cell clustering during inflammation and may control chemokine chemotactic activity.
ATRN is also known as DPPT-L, MGCA.
Associated Diseases
- Griscelli syndrome type 3
- uncombable hair syndrome
- microcephaly-albinism-digital anomalies syndrome
- oculocutaneous albinism type 3
- Tietz syndrome
- ermine phenotype
- pili bifurcati
- hypotrichosis simplex
