TRAPPC11
Description
TRAPPC11, also known as the Trafficking Protein Particle Complex subunit 11, plays a crucial role in vesicular trafficking, a fundamental cellular process responsible for transporting molecules within and outside cells. It is a component of the TRAPP complex, a large multi-protein complex essential for the formation of transport vesicles from the Golgi apparatus, the cell‘s packaging and shipping center. TRAPPC11 specifically contributes to the recruitment of tethering factors that bridge transport vesicles to their target membranes. Disruptions in TRAPPC11 function can lead to impaired protein trafficking and various cellular dysfunctions.
Associated Diseases
Did you know?
Mutations in TRAPPC11 have been linked to a rare genetic disorder called TRAPPC11-associated neurodevelopmental disorder, characterized by severe intellectual disability and developmental delays.
