SYT2

Description

The SYT2 gene encodes synaptotagmin-2, a protein that plays a crucial role in neurotransmitter release at synapses. Synaptotagmin-2 acts as a calcium sensor, triggering the fusion of synaptic vesicles with the presynaptic membrane, allowing neurotransmitters to be released into the synaptic cleft. This process is essential for communication between neurons and underlies various brain functions, including learning, memory, and movement. Mutations in the SYT2 gene have been linked to neurological disorders, highlighting its critical role in synaptic function.

Associated Diseases

• Neurodevelopmental disorders
• Epilepsy
• Autism spectrum disorder
• Intellectual disability
• Movement disorders
• Schizophrenia

Did you know?

Synaptotagmin-2 is a highly conserved protein, suggesting its importance throughout evolution.