STRADA

Description

The STRADA gene (also known as STARD7) provides instructions for making a protein that plays a crucial role in the function of mitochondria, the powerhouses of our cells. This protein, called STRADA, helps to regulate the production of energy within mitochondria by controlling the movement of lipids and cholesterol. STRADA also plays a role in mitochondrial dynamics, including their fusion and fission, processes essential for maintaining healthy mitochondrial function.

Associated Diseases

• Mitochondrial disorders: Mutations in the STRADA gene have been linked to a variety of mitochondrial disorders, including Leigh syndrome, a severe neurodegenerative disease, and other mitochondrial encephalopathies. These disorders often affect the nervous system, muscles, and other organs.
• Cardiomyopathy: STRADA mutations have also been associated with cardiomyopathy, a condition that weakens the heart muscle.
• Neurodevelopmental disorders: Some research suggests that STRADA mutations might be associated with neurodevelopmental disorders, though more research is needed.
• Ataxia: STRADA mutations can cause ataxia, a condition that affects balance and coordination.

Did you know?

The STRADA gene is named after the Italian word for "street", which reflects its role in transporting lipids and cholesterol through the cell.