PRUNE1
Description
PRUNE1 (PRUNE Homolog 1) is a gene that encodes a protein involved in the regulation of synaptic function and neuronal development. PRUNE1 protein is localized to the postsynaptic density of neurons and plays a critical role in the removal of damaged or unnecessary proteins from synapses. This process, known as synaptic pruning, is essential for the refinement and plasticity of neuronal connections during development and throughout life. Dysregulation of PRUNE1 function has been implicated in various neurological disorders, highlighting its importance in maintaining neuronal health.
Associated Diseases
Did you know?
PRUNE1 was originally discovered in the fruit fly Drosophila melanogaster, where it was shown to play a role in the development of the nervous system.
