NAXD
Description
The NAXD (NAD(P)HX dehydratase) is a protein-coding gene located on chromosome 13.
This enzyme removes water from the S-form of NAD(P)HX using energy from ATP, which is converted to ADP. Working alongside NAD(P)HX epimerase, which interconverts the S- and R-forms, NAXD enables the repair of both damaged forms of NAD(P)H. These damaged forms, known as NAD(P)HX, arise from enzymatic or heat-induced hydration reactions.
NAXD is also known as CARKD, LP3298, PEBEL2.
