MTRR : 5-methyltetrahydrofolate-homocysteine methyltransferase reductase
Description
The MTRR gene, encodes for the enzyme tetrahydrofolate reductase reductase (THFR), a crucial component in folate metabolism. THFR facilitates the conversion of dihydrofolate to tetrahydrofolate, a coenzyme essential for various metabolic processes, including DNA synthesis, repair, and methylation. Variations in the MTRR gene can impact THFR activity, potentially affecting folate levels and increasing the risk of certain health issues.
Associated Diseases
Did you know?
MTRR gene variants are linked to differences in folate metabolism, leading to variations in homocysteine levels, a biomarker associated with heart health.
